Coastal Infusion Administers Givlaari®

Givlaari (givosiran) is a prescription medicine used for the treatment of acute hepatic porphyria. Acute hepatic porphyria is a rare genetic condition in which the liver cannot properly produce a substance called haem. As a result, substances used to make haem build up in the body, causing attacks of severe abdominal pain, vomiting, and nervous system disorders.

The active substance in Givlaari, givosiran, is a synthetic small interfering RNA (a type of genetic material) that works by reducing the production of an enzyme involved in an early step of haem production in the liver.

This prevents the build-up of the substances that cause the symptoms of the condition. Givlaari successfully reduces the yearly number of serious porphyria attacks.

What It Treats

Eleprase is used to treat Acute Hepatic Porphyria.

Prescribed By

Givlaari is most often prescribed by Neurologists, Hematologists, and Geneticists.

How it’s Administered

Givlaari is administered by subcutaneous injection. Givlaari injections take only a few minutes.

Frequency

Givlaari is generally administered every four weeks.

Additional Resources

• Givlaari Website
• Prescribing Information
• Co-Pay Assistance

The information on this page is compiled from a variety of online sources. Coastal Infusion has made every effort to verify its accuracy, but patients are advised to discuss any planned or current treatments with their doctor. Report inaccuracies